How do statins affect the brain

Contributor Information Bob G. References 1. Karalis DG. Intensive lowering of low-density lipoprotein cholesterol levels for primary prevention of coronary artery disease. Mayo Clin Proc. Liao JK, Laufs U. Annu Rev Pharmacol Toxicol. The GoodRx Top Tuohy CV, Dodson J. Statins for Primary Prevention in Older Adults. Am J Cardiol. Do Statins Impair Cognition? J Gen Intern Med. Food and Drug Administration. Avoiding bias in observational studies: part 8 in a series of articles on evaluation of scientific publications.

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External link. Please review our privacy policy. FDA, , [ 6 ]. Statin labels should include cognitive impairment however the cardiovascular risks outweigh the small cognitive impairment risk. Tolerance study that resulted in one participant experiencing cognitive side effects at the mg solution dose. Case reports raise the possibility that statins may be associated with cognitive impairment in rare cases. Lovastatin treatment resulted in small performance decrements on neuropsychological tests of attention and psychomotor speed, the clinical importance of which is uncertain.

Patients given placebos performance improved more than statin patients on cognition tests given at day 0 and 6 months. There is a characterizable association between statins and cognitive impairment. M Sahebzamani, , [ 18 ]. Lipophilic statins especially atorvastatin and simvastatin have significantly more reports of Cog.

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Is a common pain reliever safe during pregnancy? Can vaping help you quit smoking? Staying Healthy Do statins increase the risk of dementia? October 1, Print This Page Click to Print. Staying Healthy. This content does not have an English version. This content does not have an Arabic version. See more conditions. Statin side effects: Weigh the benefits and risks.

Products and services. Statin side effects: Weigh the benefits and risks Statins are effective at lowering cholesterol and protecting against a heart attack and stroke, although they may lead to side effects for some people.

By Mayo Clinic Staff. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information. Please try again. Something went wrong on our side, please try again. Show references Controlling cholesterol with statins. Food and Drug Administration. Accessed Jan. Rosenson RS. Statins: Actions, side effects and administration. Rosenson RS, et al. Statin muscle-related adverse events. Ferri FF.

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American Heart Association. Statin intolerance. Rochester, Minn. Anyanwagu U, et al. Drug-induced diabetes mellitus: Evidence for statins and other drugs affecting glucose metabolism. Clinical Pharmacology and Therapeutics.

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