When is tourettes usually diagnosed
Tardive dyskinesia is a potentially irreversible neuroleptic-mediated movement disorder characterized by choreoathetoid movements that may be difficult to distinguish from tics. Haloperidol may be used in the dosage range of 0. When pimozide is used, baseline and follow-up electrocardiograms are recommended. Clonazepam has some use in the treatment of tics and Tourette's syndrome. Side effects include sedation, weight gain, impaired academic performance, social anxiety with school refusal in children and a worsening of attention in children with comorbid ADHD.
The dosage range for clonazepam is 0. Most patients with Tourette's syndrome require medication for up to one to two years. About 15 percent of patients require long-term medication for tic control.
When tics appear to be stable and adequately controlled for a period of four to six months, a slow and gradual reduction in medication, titrated to the point of emergence of functionally impairing tics, should follow.
With such a strategy, occasional drug holidays may be possible in some patients with the waning of tics. With the waxing of tics, incremental increases in medication may follow. Many patients with Tourette's syndrome have comorbid neuropsychiatric conditions, and treatment for these conditions may be necessary.
Treatment of comorbid ADHD has been controversial because of reports that stimulants hasten the onset or increase the severity of tics in some patients. In some cases, it may be necessary to treat both the ADHD and the Tourette's syndrome with a stimulant in combination with either clonidine or guanfacine, or with a neuroleptic agent.
A trial of clonidine or guanfacine alone may be sufficient to adequately treat both conditions. When possible, polypharmacy should be minimized, especially in children. Treatment of obsessive-compulsive disorder with selective serotonin reuptake inhibitors may be effective. With these medications, there is often a significant delay between initiation of treatment and optimal therapeutic response.
This response may take as long as four to six weeks. Behavior therapy is also effective in the treatment of obsessive-compulsive disorder. Figure 3 3 is a simplified scale that can be used to rate problematic behaviors, establish a baseline and determine response to intervention.
This approach is particularly helpful in children with multiple development problems. In children with chronic problems, a scale is especially helpful since it is often difficult to recall how much progress has been made. As a general rule, the parents and teachers should each complete three ratings of the child.
These data, when combined with the physician's assessment in the office, will provide a baseline of severity. The rating scale may then be used to evaluate changes in response to interventions or to monitor severity over time. Coprolalia in younger patients with Gilles de la Tourette syndrome. Mov Disord ;—5. Tics and Tourette's syndrome are not uncommon.
Family physicians are likely to be an important source of information, guidance and intervention for this disorder. Additional information for patients, parents, teachers and professionals is available from the Tourette's Syndrome Association, 42—40 Bell Blvd.
OCF , 90 Depot St. Box 70, Milford, CT ; telephone: Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. Burd received his doctorate in community health sciences from the University of Manitoba. Address correspondence to Larry Burd, Ph. Columbia Rd. Reprints are not available from the authors. American Psychiatric Association.
Burd L. Children with Tourette syndrome: a handbook for parents and teachers. Mov Disord. Jankovic J, Rohaidy H. Motor, behavioral and pharmacologic findings in Tourette's syndrome. Can J Neurol Sci. A clinical study of Gilles de la Tourette syndrome in the United Kingdom.
J Neurol Neurosurg Psychiatry. Tourette's syndrome. Tics, jerks, and quirks. Postgrad Med. Singer HS. Tic disorders. Pediatr Ann. A prevalence study of Gilles de la Tourette syndrome in North Dakota school-age children. J Am Acad Child Psych. Prevalence of Gilles de la Tourette's syndrome in North Dakota adults. Am J Psychiatry.
The natural history of Tourette syndrome: a follow-up study. Ann Neurol. Bruun RD. The natural history of Tourette syndrome. Tourette's syndrome and tic disorders: clinical understanding and treatment. New York: Wiley, Haber SN, Wolfer D. Basal ganglia peptidergic staining in Tourette syndrome. A follow-up study. Adv Neurol. Reduced basal ganglia volumes in Tourette's syndrome using three-dimensional reconstruction techniques from magnetic resonance images.
Tourette syndrome and other tic disorders. Diagnosis, pathophysiology, and treatment. Dopaminergic dysfunction in Tourette syndrome. Gilles de la Tourette syndrome after long-term chlorpromazine therapy.
Biogenic amine metabolism in Tourette syndrome. Neurobiology of Tourette syndrome. Neurol Clin. Corpus callosum morphology in children with Tourette syndrome and attention deficit hyperactivity disorder.
A twin study of Tourette syndrome. Arch Gen Psychiatry. Gilles de la Tourette's syndrome. New York: Raven, The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission.
N Engl J Med. The genetics of the Gilles de la Tourette syndrome: a review. J Lab Clin Med. Tourette syndrome: prediction of phenotypic variation in monozygotic twins by caudate nucleus D2 receptor binding. Family study and segregation analysis of Tourette syndrome: evidence for a mixed model of inheritance. Am J Hum Genet. Allen AJ.
Group streptococcal infections and childhood neuropsychiatric disorder. Curr Opin. Jankovic J. If you are the parent of a child with TS, it might be helpful to talk with other parents who have a child with the same condition, to share concerns and information. Similarly, if you are an adult with TS, talking to other adults with TS might be helpful.
Skip directly to site content Skip directly to page options Skip directly to A-Z link. Tourette Syndrome TS. Section Navigation. Facebook Twitter LinkedIn Syndicate. Diagnosing Tic Disorders. Minus Related Pages. Get Email Updates. To receive email updates about this topic, enter your email address: Email Address.
The exact cause of Tourette syndrome isn't known, but some research points to changes in the brain and problems with how nerve cells communicate.
An upset in the balance of neurotransmitters chemicals in the brain that carry nerve signals from cell to cell might play a role. Many kids and teens with Tourette syndrome have other behavioral conditions like attention deficit hyperactivity disorder ADHD , obsessive-compulsive disorder OCD , l earning disabilities, or anxiety. To be diagnosed with Tourette syndrome, a child must have several different types of tics — specifically, multiple motor tics and at least one vocal tic — for at least a year.
They may happen every day or from time to time throughout the year. A child with Tourette symptoms may need to see a neurologist, a doctor who specializes in problems with the nervous system. The neurologist may ask the child's parents to keep track of the kinds of tics involved and how often they happen. There isn't a specific diagnostic test for Tourette syndrome — instead, the health care provider diagnoses it after taking a family history, medical history, looking at the symptoms, and doing a physical exam.
Sometimes, imaging tests like magnetic resonance imaging tests MRIs , computerized tomography CT scans, electroencephalograms EEGs , or blood tests can rule out other conditions that might cause symptoms similar to Tourette syndrome.
Just as Tourette syndrome is different for every person, treatment can be different, too. While there isn't a cure for Tourette syndrome, most tics don't get in the way of day-to-day life. If they do, doctors may suggest medicines to help control symptoms. Tourette syndrome is not a psychological condition, but doctors sometimes refer kids and teens to a psychologist or psychiatrist. Seeing a therapist won't stop their tics, but it can help to talk to someone about their problems, cope with stress better, and learn relaxation techniques.
Tics usually are most severe before the mid-teen years. Most people see great improvement in their late teens to early adulthood, though some will have their tics continue into adulthood. Many people don't understand what Tourette syndrome is or what causes it, so they might not know how to act around someone who has tics. If people stare or comment, kids and teens with Tourette syndrome can feel embarrassed and frustrated. Someone who has it might have to explain the condition to others or deal with teasing or gawking.
0コメント